Acquisition and Use of Common Ground in Communication

FUNDING

F32 NIH DC008825; 9/2006  – 8/2009

PROJECT ABSTRACT

The goal of this project is to contribute to the understanding of the neural basis for and relationship between memory and language, by investigating the acquisition and use of “common ground” in communication. The experimental approach uses the lesion method to interrelate neuropsychological and neuroanatomical findings, using both group studies and multiple single-case studies of neurological patients with focal brain lesions. The proposed work builds on an exciting finding from my doctoral work: severely amnesic patients can acquire common ground (shared referential labels used to facilitate rapid and efficient communication) in regular interactions with familiar partners. The crucial cognitive components and neuroanatomical correlates of this learning, however, have yet to be determined. One principle aim here is to define and characterize those cognitive and neural mechanisms supporting common ground in communication. The nature of the task used in my experimental work involves “real-world” learning and communication. The fact that individuals with amnesia performed so well in this truly real-world type of collaborative interaction is very exciting with respect to rehabilitation possibilities. The second aim of this work is to test the clinical efficacy of this paradigm by designing and implementing a collection of single case intervention studies using the collaborative referencing task in patients with circumscribed impairments of learning and memory, aimed at improving their daily functioning.

KEY FINDINGS

Duff, M.C., Hengst, J., Tranel, D., & Cohen, N.J. (2006). Development of shared information in communication despite hippocampal amnesia. Nature Neuroscience, 9 (1), 140-146.

 

Duff, M.C., Hengst, J., Tranel, D., & Cohen, N.J. (2008). Collaborative discourse facilitates efficient communication and new semantic learning in amnesia. Brain and Language, 106 (1), 41-54

 

Gupta, R., Duff, M.C., & Tranel, D. (2011). Bilateral amygdala damage impairs the acquisition and use of common ground in social interaction. Neuropsychology, 25 (2), 137-146.

 

Duff, M.C., Warren, D., Gupta, R., Benabe Vidal, J.P., Tranel, D., & Cohen, N.J. (2011). Teasing apart tangrams: testing hippocampal pattern separation with a collaborative referencing paradigm. Hippocampus, 22, 1087-1091

 

Gupta, R., Tranel, D., & Duff, M.C. (2012). Ventromedial prefrontal cortex damage does not impair the development and use of common ground in social interaction: Implications for cognitive theory of mind. Neuropsychologia, 25 (2), 137-146.

 

Duff, M.C., Gallegos, D., Cohen, N.J. & Tranel, D. (2013).  Learning in Alzheimer’s disease is facilitated by social interaction and common ground. Journal of Comparative Neurology, 521 (18), 4356-4369.

 

Gupta Gordon, R., Duff, M.C., & Cohen, N.J. (2018). Applications of Collaborative memory: Patterns of success and failure in individuals with hippocampal amnesia. In M. Meade, A. Barnier, P. Van Bergen, C. Harris, & J. Sutton (Eds.) Collaborative remembering: How remembering with others influences memory.